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The Impact of Mechanical Forces in Heart Morphogenesis

1 Feb 2012

Abstract excerpt

C ongenital heart disease (CHD) is the most common birth defect in humans and results from deficient cardiac development, a complex process that is not completely understood. The heart starts to function before its morphogenesis is complete and the increasing needs of the growing embryo for oxygen and nutrients demand a proportional increase in the performance of the organ. We review recent findings supporting...

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PMID: 22337926
DOI: 10.1161/circgenetics.111.961086

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