Article
Prevalence of etravirine resistance associated mutations in HIV-1 strains isolated from infected individuals failing efavirenz: comparison between subtype B and non-B genetic variants.
Journal of medical virology - 1 Apr 2012
Pereira-Vaz João, Duque Vitor, Pereira Branca, Mota Vanda, Morais Célia, Saraiva-da-Cunha José, Meliço-Silvestre António
Abstract excerpt
Etravirine (ETR) is a non-nucleoside analogue reverse transcriptase inhibitor (NNRTI) with a high genetic barrier to the development of resistance and with potential activity against Human immunodeficiency virus type 1 (HIV-1) strains resistant to first-generation NNRTIs. The objective of this study was to investigate the prevalence of ETR resistance associated mutations (RAMs) in HIV-1 strains isolated from...
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