Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interferon-γ-producing immature myeloid cells confer protection against severe invasive group A Streptococcus infections.

Nature communications - 14 Feb 2012

Matsumura Takayuki, Ato Manabu, Ikebe Tadayoshi, Ohnishi Makoto, Watanabe Haruo, Kobayashi Kazuo

Abstract excerpt

Cytokine-activated neutrophils are known to be essential for protection against group A Streptococcus infections. However, during severe invasive group A Streptococcus infections that are accompanied by neutropenia, it remains unclear which factors are protective against such infections, and whic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD11b Antigen
Share to Immune System
Share to Mice, Inbred C3H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myeloid Cells

Share to Neutropenia

Share to Nitric Oxide

Share to Streptococcal Infections

Share to Streptococcus pyogenes

Source

Open in PubMed Open full text

Identifiers

PMID: 22334081
DOI: 10.1038/ncomms1677
PMCID: PMC3293428

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22334081-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon-γ-producing immature myeloid cells confer protection against severe invasive group A Streptococcus infections.PMID 22334081Read ↗

Responses of innate immune cells to group A StreptococcusSemantic proximity Read ↗

IFN-γ primes bone marrow neutrophils to acquire regulatory functions in severe viral respiratory infectionsSemantic proximity Read ↗

IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of Legionella pneumophilaSemantic proximity Read ↗

The severity of Streptococcus pyogenes infections in children is significantly associated with plasma levels of inflammatory cytokines.Semantic proximity Read ↗

In vivo interferon-gamma induced changes in gene expression dramatically alter neutrophil phenotype.Semantic proximity Read ↗

Exacerbated Type II Interferon Response Drives Hypervirulence and Toxic Shock by an Emergent Epidemic Strain of Streptococcus suisSemantic proximity Read ↗

Protection conferred by intraperitoneal Group A <i>Streptococcus</i> immunization relies on macrophages and IFN-γ but not on concurrent adaptive immune responsesSemantic proximity Read ↗

Neutrophils that infiltrate the central nervous system regulate T cell responses.Semantic proximity Read ↗

Complex Immune Cell Interplay in the Gamma Interferon Response during Toxoplasma gondii InfectionSemantic proximity Read ↗

Interleukin-1 promotes coagulation, which is necessary for protective immunity in the lung against Streptococcus pneumoniae infection.Semantic proximity Read ↗

Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization.Semantic proximity Read ↗

Regulation and role of IFN-gamma in the innate resistance to infection with Chlamydia pneumoniae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.