Article
Laser captured hepatocytes show association of butyrylcholinesterase gene loss and fibrosis progression in hepatitis C-infected drug users.
Hepatology (Baltimore, Md.) - 1 Aug 2012
Munshaw Supriya, Hwang Hyon S, Torbenson Michael, Quinn Jeffrey, Hansen Kasper D, Astemborski Jacquie, Mehta Shruti H, Ray Stuart C, Thomas David L, Balagopal Ashwin
Abstract excerpt
UNLABELLED: Chronic hepatitis C virus (HCV) infection is complicated by hepatic fibrosis. Hypothesizing that early fibrogenic signals may originate in cells susceptible to HCV infection, hepatocyte gene expression was analyzed from persons with chronic HCV at different stages of liver fibrosis. Four HCV-infected subjects with precirrhosis liver fibrosis (Ishak fibrosis 3-5) were matched for age, race, and gender...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.