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Immune Subversion and Quorum-Sensing Shape the Variation in Infectious Dose among Bacterial Pathogens

2 Feb 2012

Abstract excerpt

Many studies have been devoted to understand the mechanisms used by pathogenic bacteria to exploit human hosts. These mechanisms are very diverse in the detail, but share commonalities whose quantification should enlighten the evolution of virulence from both a molecular and an ecological perspective. We mined the literature for experimental data on infectious dose of bacterial pathogens in humans (ID50) and also...

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PMID: 22319444
DOI: 10.1371/journal.ppat.1002503

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