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Article

The T788G mutation in the cyp51C gene confers voriconazole resistance in Aspergillus flavus causing aspergillosis.

Antimicrobial agents and chemotherapy - 1 May 2012

Liu Wei, Sun Yi, Chen Wei, Liu Weixia, Wan Zhe, Bu Dingfang, Li Ruoyu

Abstract excerpt

With voriconazole (VRC) being approved as the first choice in treating invasive aspergillosis (IA) and its increasing use in treatment, a VRC-resistant strain of Aspergillus flavus, the second leading cause of IA after Aspergillus fumigatus, has emerged. The VRC-resistant strain of A. flavus was isolated for the first time from the surgical lung specimen of an IA patient with no response to VRC therapy. In order...

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Identifiers

PMID: 22314539
DOI: 10.1128/AAC.05477-11
PMCID: PMC3346632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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