Takayasu's arteritis is associated with HLA-B*52, but not with HLA-B*51, in Turkey.

doi:10.1186/ar3730

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Article

Takayasu's arteritis is associated with HLA-B52, but not with HLA-B51, in Turkey.

Arthritis research & therapy - 6 Feb 2012

Sahin Ziver, Bıcakcıgil Muge, Aksu Kenan, Kamali Sevil, Akar Servet, Onen Fatos, Karadag Omer, Ozbalkan Zeynep, Ates Askin, Ozer Huseyin Te, Yilmaz Vuslat, Seyahi Emire, Ozturk Mehmet A, Cefle Ayse, Cobankara Veli, Onat A Mesut, Tunc Ercan, Düzgün Nursen, Aydin Sibel Z, Yilmaz Neslihan, Fresko İzzet, Karaaslan Yasar, Kiraz Sedat, Akkoc Nurullah, Inanc Murat, Keser Gokhan, Uyar F Aytul, Direskeneli Haner, Saruhan-Direskeneli Güher

Abstract excerpt

INTRODUCTION: HLA-B*51 and HLA-B*52 are two close human leukocyte antigen (HLA) allele groups with minor amino acid differences. However, they are associated with two different vasculitides (HLA-B*51 in Behçet's disease and HLA-B*52 in Takayasu's arteritis (TAK)) and with major clinical and immunological differences. In this study, we aimed to screen a large cohort of TAK patients from Turkey for the presence of...

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PMID: 22309845
DOI: 10.1186/ar3730
PMCID: PMC3392822

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