Article
Comprehensive analysis of HLA genes in Takayasu arteritis in Japan.
International journal of cardiology - 1 Aug 1996
Kimura A, Kitamura H, Date Y, Numano F
Abstract excerpt
To identify an HLA-linked susceptibility gene to Takayasu's arteritis, comprehensive analysis of HLA genes was performed. By serologic HLA typing, positive associations of Takayasu's arteritis with HLA-B52 and B39 were observed. The DNA typing of HLA-B gene and class II genes (DRB1, DQA1, DPB1) s...
Topics
- Alleles
- Amino Acid Sequence
- Gene Frequency
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- HLA Antigens
- HLA-B Antigens
- Histocompatibility Antigens Class II
- Histocompatibility Testing
- Humans
- Japan
- Linkage Disequilibrium
- Molecular Sequence Data
- Polymerase Chain Reaction
- Takayasu Arteritis
