Article
[Susceptibility HLA alleles and amino acids to Takayasu arteritis].
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology - 1 Jan 2014
Terao Chikashi, Yoshifuji Hajime, Mimori Tsuneyo, Matsuda Fumihiko
Abstract excerpt
Takayasu arteritis (TAK) is a systemic vasculitis affecting aorta and its large branches which were firstly reported from Japan. TAK develops mainly in young females and the number of patients with TAK in Japan is estimated about 6,000 to 10,000. This low prevalence has made genetic studies of TAK difficult to elucidate its genetic background. The HLA region, especially HLA-B locus, is the strongest...
Topics
- Alleles
- Amino Acids
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- HLA-B Antigens
- Humans
- Takayasu Arteritis