Aberrant action of amyloidogenic host defense peptides: a new paradigm to investigate neurodegenerative disorders?

Abstract excerpt

Host defense peptides (HDPs) are components of the innate immune system with activity against a broad range of microbes. In some cases, it appears that this activity is mediated by the ability of these peptides to permeabilize microbial membranes via the formation of amyloid associated structures. Recent evidence suggests that the naturally occurring function of the Aβ40 and Aβ42 peptides, which are causative...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alzheimer's disease research and treatments
• Share to Antimicrobial Peptides and Activities
• Share to Machine Learning in Bioinformatics