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Article

A functional variation in the hypocretin neuropeptide precursor gene may be associated with obstructive sleep apnea syndrome in Japan.

The Laryngoscope - 1 Apr 2012

Ahmed Wael A, Tsutsumi Makiko, Nakata Seiichi, Mori Terumi, Nishimura Yoichi, Fujisawa Toshiyuki, Kato Ichiro, Nakashima Mayuki, Kurahashi Hiroki, Suzuki Kenji

Abstract excerpt

OBJECTIVES/HYPOTHESIS: To evaluate the association of hypocretin neuropeptide precursor gene (HCRT) variations with obstructive sleep apnea syndrome (OSAS) in a cohort of Japanese patients and to further evaluate whether the significant HCRT variations have potential functional consequences on HCRT expression. STUDY DESIGN: Case-control genetic association study. METHODS: We studied the genetic variations within...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22302634
DOI: 10.1002/lary.23179

Genes

HCRT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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