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Article

Glycomacropeptide, a low-phenylalanine protein isolated from cheese whey, supports growth and attenuates metabolic stress in the murine model of phenylketonuria.

American journal of physiology. Endocrinology and metabolism - 1 Apr 2012

Solverson Patrick, Murali Sangita G, Brinkman Adam S, Nelson David W, Clayton Murray K, Yen Chi-Liang Eric, Ney Denise M

Abstract excerpt

Phenylketonuria (PKU) is caused by a mutation in the phenylalanine (phe) hydroxylase gene and requires a low-phe diet plus amino acid (AA) formula to prevent cognitive impairment. Glycomacropeptide (GMP) contains minimal phe and provides a palatable alternative to AA formula. Our objective was to compare growth, body composition, and energy balance in Pah(enu2) (PKU) and wild-type mice fed low-phe GMP, low-phe...

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Identifiers

PMID: 22297302
DOI: 10.1152/ajpendo.00647.2011
PMCID: PMC3330708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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