Article
Differential association between the norepinephrine transporter gene and ADHD: role of sex and subtype.
Journal of psychiatry & neuroscience : JPN - 1 Feb 2012
Sengupta Sarojini M, Grizenko Natalie, Thakur Geeta A, Bellingham Johanne, DeGuzman Rosherrie, Robinson Sandra, TerStepanian Marina, Poloskia Anna, Shaheen S M, Fortier Marie-Eve, Choudhry Zia, Joober Ridha
Abstract excerpt
BACKGROUND: Pharmacologic and animal studies have strongly implicated the norepinephrine transporter (NET) in the pathophysiology of attention-deficit/hyperactivity disorder (ADHD). We conducted a family-based study, with stratification based on sex and subtype, to test the association between 30 tag single-nucleotide polymorphisms (SNPs) within the gene encoding NET (SLC6A2) and ADHD. METHODS: Family-based...
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