Article
Effects of norepinephrine transporter gene variants on NET binding in ADHD and healthy controls investigated by PET.
Human brain mapping - 1 Mar 2016
Sigurdardottir Helen L, Kranz Georg S, Rami-Mark Christina, James Gregory M, Vanicek Thomas, Gryglewski Gregor, Kautzky Alexander, Hienert Marius, Traub-Weidinger Tatjana, Mitterhauser Markus, Wadsak Wolfgang, Hacker Marcus, Rujescu Dan, Kasper Siegfried, Lanzenberger Rupert
Abstract excerpt
Attention deficit hyperactivity disorder (ADHD) is a heterogeneous disorder with a strong genetic component. The norepinephrine transporter (NET) is a key target for ADHD treatment and the NET gene has been of high interest as a possible modulator of ADHD pathophysiology. Therefore, we conducted an imaging genetics study to examine possible effects of single nucleotide polymorphisms (SNPs) within the NET gene on...
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