Article
Replication of a rare protective allele in the noradrenaline transporter gene and ADHD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2008
Xu X, Hawi Z, Brookes K J, Anney R, Bellgrove M, Franke B, Barry E, Chen W, Kuntsi J, Banaschewski T, Buitelaar J, Ebstein R, Fitzgerald M, Miranda A, Oades R D, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen H-C, Faraone S V, Gill M, Asherson P
Abstract excerpt
Replication is a key to resolving whether a reported genetic association represents a false positive finding or an actual genetic risk factor. In a previous study screening 51 candidate genes for association with ADHD in a multi-centre European sample (the IMAGE project), two single nucleotide polymorphisms (SNPs) within the norepinephrine transporter (SLC6A2) gene were found to be associated with attention...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.