Article
Cilostazol induces cellular senescence and confers resistance to etoposide-induced apoptosis in articular chondrocytes.
International journal of molecular medicine - 1 Apr 2012
Kim Kang Mi, Kim Jong Min, Yoo Young Hyun, Kim Jeung Il, Park Young Chul
Abstract excerpt
We recently reported that cilostazol protects chondrocytes against stress-induced apoptosis and prevents cartilage destruction in an osteoarthritis (OA) model. In the present study, we elucidate the mechanism underlying the protective effect induced by cilostazol against stress-induced apoptosis in chondrocytes. Cilostazol significantly reduced the expression of...
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