Article
A flexible Bayesian model for studying gene-environment interaction.
PLoS genetics - 1 Jan 2012
Yu Kai, Wacholder Sholom, Wheeler William, Wang Zhaoming, Caporaso Neil, Landi Maria Teresa, Liang Faming
Abstract excerpt
An important follow-up step after genetic markers are found to be associated with a disease outcome is a more detailed analysis investigating how the implicated gene or chromosomal region and an established environment risk factor interact to influence the disease risk. The standard approach to this study of gene-environment interaction considers one genetic marker at a time and therefore could misrepresent and...
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