Article
Possible association between polymorphisms of human vascular endothelial growth factor A gene and susceptibility to glioma in a Chinese population.
International journal of cancer - 1 Jan 2011
Li Rui, Zhao Yao, Fan Weiwei, Chen Hongyan, Chen Yuanyuan, Liu Yanhong, Chen Gong, Zhou Keke, Huang Fengping, Mao Ying, Zhou Liangfu, Lu Daru, Shugart Yin Yao
Abstract excerpt
Vascular endothelial growth factor A (VEGFA), one of the most predominant mediators of pathologic angiogenesis, plays a critical role in glioma carcinogenesis and development via promoting tumor growth. We hypothesized that VEGFA polymorphisms may influence glioma risk. We recently genotyped 9 VEGFA single-nucleotide polymorphisms (SNPs) in 766 glioma patients and 824 cancer-free controls selected from a Chinese...
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