Genotyping of Mycobacterium leprae for understanding the distribution and transmission of leprosy in endemic provinces of China.

doi:10.1016/j.ijid.2020.06.032

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Article

Genotyping of Mycobacterium leprae for understanding the distribution and transmission of leprosy in endemic provinces of China.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Sept 2020

Chokkakula Santosh, Shui Tiejun, Jiang Haiqin, Yang Jun, Li Xiong, He Jun, Shen Limei, Liu Jie, Wang De, Suryadevara Naveen Chandra, Pathakumari Balaji, Wang Le, Chen Yanqing, Shi Ying, Zhang Wenyue, Wang Hao, Chen Huan, Kuang Yanfei, Li Bin, Yua Meiwen, Yan Liangbin, Vissa Varalakshmi, Tsang Lemuel Shui Lun, Li Jinlan, Wang Hongsheng

Abstract excerpt

OBJECTIVES: Understanding the nature of Mycobacterium leprae transmission is vital to implement better control strategies for leprosy elimination. The present study expands the knowledge of county-level strain diversity, distribution, and transmission patterns of leprosy in endemic provinces of China. METHODS: We genetically characterized 290 clinical isolates of M. leprae from four endemic provinces using...

Topics

Alleles
China
Cluster Analysis
DNA, Bacterial
Genotype
Geography
Humans
Leprosy
Minisatellite Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Epidemiology

Mycobacterium leprae

Phylogeny

Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 32553715
DOI: 10.1016/j.ijid.2020.06.032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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