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Article

Three-dimensional analysis of ribonucleoprotein complexes in influenza A virus

24 Jan 2012

Abstract excerpt

The influenza A virus genome consists of eight single-stranded negative-sense RNA (vRNA) segments. Although genome segmentation provides advantages such as genetic reassortment, which contributes to the emergence of novel strains with pandemic potential, it complicates the genome packaging of progeny virions. Here we elucidate, using electron tomography, the three-dimensional structure of ribonucleoprotein...

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PMID: 22273677
DOI: 10.1038/ncomms1647

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