Article
Molecular dynamics studies of the nucleoprotein of influenza A virus: role of the protein flexibility in RNA binding.
PloS one - 1 Jan 2012
Tarus Bogdan, Chevalier Christophe, Richard Charles-Adrien, Delmas Bernard, Di Primo Carmelo, Slama-Schwok Anny
Abstract excerpt
The influenza viruses contain a segmented, negative stranded RNA genome. Each RNA segment is covered by multiple copies of the nucleoprotein (NP). X-ray structures have shown that NP contains well-structured domains juxtaposed with regions of missing electron densities corresponding to loops. In...
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