Article
Analysis of the PKR-eIF2alpha phosphorylation homology domain (PePHD) of hepatitis C virus genotype 1 in HIV-coinfected patients by ultra-deep pyrosequencing and its relationship to responses to pegylated interferon-ribavirin treatment.
Archives of virology - 1 Apr 2012
Bolcic F, Sede M, Moretti F, Westergaard G, Vazquez M, Laufer N, Quarleri J
Abstract excerpt
Chronic coinfection with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) is among the greatest challenges facing public health worldwide. In this population, the response to hepatitis C therapy by treatment with pegylated interferon plus ribavirin (PEG-IFN+RBV) is lower than in HCV-monoinfected patients, particularly in those infected by HCV genotype 1. A PKR/eIF-2α phosphorylation homology domain...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.