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Article

Mutations in the E2 and NS5A regions in patients infected with hepatitis C virus genotype 1a and their correlation with response to treatment.

Journal of medical virology - 1 Aug 2011

Yahoo Neda, Sabahi Farzaneh, Shahzamani Kiana, Malboobi Mohamad Ali, Jabbari Hossain, Sharifi Houshang, Mousavi-Fard Seyed Hossein, Merat Shahin

Abstract excerpt

Heterogeneity of subgenomic regions of hepatitis C virus (HCV) may be associated with response to interferon (IFN) therapy. The amino acid sequences of the PKR/eIF-2α phosphorylation homology domain (pePHD), IFN sensitivity determining region (ISDR), PKR binding domain (PKRBD), and variable region 3 (V3) were studied in 19 patients before and after 4 weeks of treatment. All patients were infected with HCV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21678437
DOI: 10.1002/jmv.22144

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Mutations in the E2 and NS5A regions in patients infected with hepatitis C virus genotype 1a and their correlation with response to treatment.PMID 21678437Read ↗

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