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Article

Glycosaminoglycans mimetics potentiate the clonogenicity, proliferation, migration and differentiation properties of rat mesenchymal stem cells.

Stem cell research - 1 Mar 2012

Frescaline Guilhem, Bouderlique Thibault, Huynh Minh Bao, Papy-Garcia Dulce, Courty José, Albanese Patricia

Abstract excerpt

Successful use of stem cell-based therapeutic products is conditioned by transplantation of optimized cells in permissive microenvironment. Mesenchymal stem cell (MSC) fates are tightly regulated by humoral factors, cellular interactions and extracellular matrix (ECM) components, such as glycosaminoglycans (GAG), which are complex polysaccharides with structural heterogeneity. During osteogenesis, a temporally...

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Identifiers

PMID: 22265738
DOI: 10.1016/j.scr.2011.09.005

Genes

MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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