Article
The association of apolipoprotein E polymorphism and lipid levels in children with a family history of premature coronary artery disease.
Journal of clinical lipidology - 1 Jan 2000
Ciftdoğan Dilek Yılmaz, Coskun Senol, Ulman Cevval, Tıkız Hakan
Abstract excerpt
BACKGROUND: Polymorphisms in the apolipoprotein E (apoE) gene may modulate lipoprotein metabolism and influence plasma lipid levels. Thus, they have been associated with relative risk of coronary artery disease (CAD). OBJECTIVE: To evaluate the association of apolipoprotein E polymorphism and lipid levels in children with family history of premature coronary artery disease. METHODS: The apoE genotypes, allele...
Topics
- Adolescent
- Alleles
- Apolipoprotein E4
- Case-Control Studies
- Child
- Child, Preschool
- Cholesterol
- Cholesterol, LDL
- Coronary Artery Disease
- DNA Mutational Analysis
- Female
- Gene Frequency
- Genetic Association Studies
- Genotype
- Humans
- Male
- Polymorphism, Genetic