Article
HIV type 1 coreceptor tropism, CCR5 genotype, and integrase inhibitor resistance profiles in Vietnam: implications for the introduction of new antiretroviral regimens.
AIDS research and human retroviruses - 1 Oct 2012
Luu Quynh Phuong, Dean Jonathan, Do Trinh Thi Diem, Carr Michael J, Dunford Linda, Coughlan Suzie, Connell Jeff, Nguyen Hien Tran, Hall William W, Nguyen Thi Lan Anh
Abstract excerpt
In Vietnam, where an estimated 280,000 people will be HIV-positive by 2012, recommended antiretroviral regimens do not include more recently developed therapeutics, such as Integrase inhibitors (INI) and coreceptor antagonists. This study examined HIV-1 coreceptor tropism and INI drug resistance profiles, in parallel with CCR5 genotypes, in a cohort of 60 HIV-positive individuals from different regions of...
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