Article
Changes in bicoid mRNA anchoring highlight conserved mechanisms during the oocyte-to-embryo transition.
Current biology : CB - 22 Jul 2008
Weil Timothy T, Parton Richard, Davis Ilan, Gavis Elizabeth R
Abstract excerpt
Intracellular mRNA localization directs protein synthesis to particular subcellular domains to establish embryonic polarity in a variety of organisms. In Drosophila, bicoid (bcd) mRNA is prelocalized at the oocyte anterior. After fertilization, translation of this RNA produces a Bcd protein gradient that determines anterior cell fates [1] and [2]. Analysis of bcd mRNA during late stages of oogenesis suggested a...
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