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Article

Common genetic risk variants of TLR2 are not associated with periodontitis in large European case-control populations.

Journal of clinical periodontology - 1 Apr 2012

Richter Gesa M, Graetz Christian, Pohler Pia, Nothnagel Michael, Dommisch Henrik, Laine Marja L, Folwaczny Mathias, Noack Barbara, Eickholz Peter, Groessner-Schreiber Birte, Jepsen Søren, Loos Bruno G, Schreiber Stefan, Schaefer Arne S

Abstract excerpt

AIM: Involvement of TLR2 in the pathophysiology of periodontitis has widely been discussed, but hitherto, no validated genetic associations were reported. Previous association studies lacked sufficient statistical power and adequate haplotype information to draw unambiguous conclusions. The aim of this study was to comprehensively investigate TLR2 linkage disequilibrium (LD) regions for their potential...

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Source

Identifiers

PMID: 22251071
DOI: 10.1111/j.1600-051X.2011.01846.x

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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