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Meso-Endothelial Bipotent Progenitors from Human Placenta Display Distinct Molecular and Cellular Identity

1 Mar 2018

Abstract excerpt

The existence of bipotential precursors for both mesenchymal and endothelial stem/progenitor cells in human postnatal life is debated. Here, we hypothesized that such progenitors are present within the human term placenta. From a heterogeneous placental single-cell suspension, a directly flow-sorted CD45 − CD34 + CD144 + CD31Lo population uniquely differentiated into both endothelial and mesenchymal colonies in...

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PMID: 29478891
DOI: 10.1016/j.stemcr.2018.01.011

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