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Role of Mycobacterium tuberculosis pknD in the Pathogenesis of central nervous system tuberculosis

13 Jan 2012

Abstract excerpt

BACKGROUND: Central nervous system disease is the most serious form of tuberculosis, and is associated with high mortality and severe neurological sequelae. Though recent clinical reports suggest an association of distinct Mycobacterium tuberculosis strains with central nervous system disease, the microbial virulence factors required have not been described previously. RESULTS: We screened 398 unique M....

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PMID: 22243650
DOI: 10.1186/1471-2180-12-7

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