Article
MMP1 and MMP20 contribute to tooth agenesis in humans.
Archives of oral biology - 1 May 2011
Küchler Erika C, Menezes Renato, Callahan Nicholas, Costa Marcelo C, Modesto Adriana, Meira Raquel, Patir Asli, Seymen Figen, Paiva Katiúcia B S, Nunes Fabio Daumas, Granjeiro José Mauro, Vieira Alexandre R
Abstract excerpt
OBJECTIVE: Variations in genes that are critical for tooth formation may contribute to the tooth agenesis. MMPs are potential candidate genes for dental alterations based on the roles they play during embryogenesis. The aim of this study was to investigate the possible association between MMP1, MMP3, and MMP20 and tooth agenesis. METHODS: One hundred sixty-seven nuclear families from two different populations...
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