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Article

Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm.

PloS one - 1 Jan 2012

Schröder Elisabeth, Gebel Lena, Eremeev Andrey A, Morgner Jessica, Grum Daniel, Knauer Shirley K, Bayer Peter, Mueller Jonathan W

Abstract excerpt

In higher eukaryotes, PAPS synthases are the only enzymes producing the essential sulphate-donor 3'-phospho-adenosine-5'-phosphosulphate (PAPS). Recently, PAPS synthases have been associated with several genetic diseases and retroviral infection. To improve our understanding of their pathobiological functions, we analysed the intracellular localisation of the two human PAPS synthases, PAPSS1 and PAPSS2. For both...

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Source

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Identifiers

PMID: 22242175
DOI: 10.1371/journal.pone.0029559
PMCID: PMC3252339

Genes

PAPSS1
PAPSS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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