Article
Determinants of per-coital-act HIV-1 infectivity among African HIV-1-serodiscordant couples.
The Journal of infectious diseases - 1 Feb 2012
Hughes James P, Baeten Jared M, Lingappa Jairam R, Magaret Amalia S, Wald Anna, de Bruyn Guy, Kiarie James, Inambao Mubiana, Kilembe William, Farquhar Carey, Celum Connie
Abstract excerpt
BACKGROUND: Knowledge of factors that affect per-act infectivity of human immunodeficiency virus type 1 (HIV-1) is important for designing HIV-1 prevention interventions and for the mathematical modeling of the spread of HIV-1. METHODS: We analyzed data from a prospective study of African HIV-1-serodiscordant couples. We assessed transmissions for linkage within the study partnership, based on HIV-1 sequencing....
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