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New type of Bcr/Abl junction in Philadelphia chromosome-positive chronic myelogenous leukemia

1 Nov 1990

Abstract excerpt

A new and rare type of Bcr/Abl junction between exon C3 of the 3' portion of the Bcr gene and Abl exon 2 has been identified in the leukemic cells of two Ph1-positive chronic myelogenous leukemia patients in chronic phase. This is the fourth type of Bcr/Abl junction so far identified in Ph1-positive hematologic malignancies and is a consequence of an unusual breakpoint position on chromosome 22 that falls...

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PMID: 2224129
DOI: 10.1182/blood.v76.9.1819.1819

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