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Article

AatA Is a Novel Autotransporter and Virulence Factor of Avian Pathogenic Escherichia coli

23 Dec 2009

Abstract excerpt

Autotransporters (AT) are widespread in Gram-negative bacteria, and many of them are involved in virulence. An open reading frame (APECO1_O1CoBM96) encoding a novel AT was located in the pathogenicity island of avian pathogenic Escherichia coli (APEC) O1's virulence plasmid, pAPEC-O1-ColBM. This 3.5-kb APEC autotransporter gene (aatA) is predicted to encode a 123.7-kDa protein with a 25-amino-acid signal peptide,...

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PMID: 20028805
DOI: 10.1128/iai.00513-09

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