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Article

MicroRNAs and depression.

Neurobiology of disease - 1 May 2012

Mouillet-Richard Sophie, Baudry Anne, Launay Jean-Marie, Kellermann Odile

Abstract excerpt

With an estimated life-time prevalence of 15 to 17% and an incapacitating illness in 50% of cases, depressive spectrum disorders represent a heavy public health burden. Despite considerable efforts to underpin the molecular and cellular changes associated with depressive states, a global understanding of the pathophysiology of major depressive disorders (MDD) is still lacking. It is now acknowledged that deficits...

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PMID: 22226785
DOI: 10.1016/j.nbd.2011.12.035

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