Article
Association of a TANK gene polymorphism with outcomes of hepatitis B virus infection in a Chinese Han population.
Viral immunology - 1 Feb 2012
Song Qi-Long, He Xing-Xing, Yang Hong, Li Jin, Chen Man, Wang Meng-Yi, Liu Qing, Yu Jin-Ling, Yao Jin-Jian, Liu Li-Feng, Sun Shu-Zhen, Lin Ju-Sheng
Abstract excerpt
The host genetic compound plays a vital role in determining clinical outcomes of hepatitis B virus (HBV) infection. The tumor necrosis factor receptor-associated factor family member-associated nuclear factor-κB (NF-κB) activator (TANK) takes part in the tumor necrosis factor-α (TNF-α)-mediated NF-κB signaling pathway and the interferon (IFN)-induction pathways that have relevance to HBV-related liver disease. In...
Topics
- Adaptor Proteins, Signal Transducing
- Asian People
- Carcinoma, Hepatocellular
- Carrier State
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
