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Article

Interactive effects of ATOH7 and RFTN1 in association with adult-onset primary open-angle glaucoma.

Investigative ophthalmology & visual science - 16 Feb 2012

Chen Jian-Huan, Wang Degui, Huang Chukai, Zheng Yuqian, Chen Haoyu, Pang Chi-Pui, Zhang Mingzhi

Abstract excerpt

PURPOSE: Genome-wide association studies have shown association of the atonal homolog 7 (ATOH7) and raftlin lipid raft linker 1 (RFTN1) genes with glaucoma-related optic disc parameters. ATOH7 and RFTN1 sequence variations were investigated in patients with primary open-angle glaucoma (POAG) and their relationships with vertical cup-to-disc ratio (VCDR) and central corneal thickness (CCT) were determined....

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Source

Identifiers

PMID: 22222511
DOI: 10.1167/iovs.11-8277

Genes

ATOH7
RFTN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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