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Article

Mutational analysis of the RB1 gene in Moroccan patients with retinoblastoma.

Molecular vision - 1 Jan 2011

Abidi Omar, Knari Sara, Sefri Hajar, Charif Majida, Senechal Audrey, Hamel Christian, Rouba Hassan, Zaghloul Khalid, El Kettani Asmaa, Lenaers Guy, Barakat Abdelhamid

Abstract excerpt

PURPOSE: Retinoblastoma (RB), the most common intraocular tumor occurring in infancy and early childhood, is most often related to mutations in the RB1 gene. In this study, we screened the RB1 germline mutations in 41 unrelated Moroccan patients with retinoblastoma, 25 heritable cases, and 16 sporadic unilateral cases. METHODS: After complete ophthalmic examinations were performed and consent obtained, DNA was...

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Identifiers

PMID: 22219649
PMCID: PMC3250372

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Source receipt: pubmed, retrieved 7 Sept 2026.

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