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Generation of induced pluripotent stem cells from large domestic animals

25 Jun 2020

Abstract excerpt

BACKGROUND: Induced pluripotent stem cells (iPSCs) have enormous potential in developmental biology studies and in cellular therapies. Although extensively studied and characterized in human and murine models, iPSCs from animals other than mice lack reproducible results. METHODS: Herein, we describe the generation of robust iPSCs from equine and bovine cells through lentiviral transduction of murine or human...

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PMID: 32586372
DOI: 10.1186/s13287-020-01716-5

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