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Article

<i>TET2</i> and <i>DNMT3A</i> Mutations in Human T-Cell Lymphoma

5 Jan 2012

Abstract excerpt

A substantial fraction of T-cell lymphomas carry mutations in two genes — TET2 and DNMT3A — that are involved in DNA methylation. The co-occurrence of these mutations suggests that inhibitors of DN...

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Share to Cancer-related gene regulation
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Identifiers

PMID: 22216861
DOI: 10.1056/nejmc1111708

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Related research

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<i>TET2</i> and <i>DNMT3A</i> Mutations in Human T-Cell LymphomaPMID 22216861Read ↗

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A Therapeutic Strategy for Preferential Targeting of TET2-Mutant and TET Dioxygenase–Deficient Cells in Myeloid NeoplasmsSemantic proximity Read ↗

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[Dual epigenetic therapy in TET2 gene positive extranodal peripheral T-cell lymphoma with follicular helper T-cell (TFH) phenotype: a case report and literature review].Semantic proximity Read ↗

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