Article
Fine-mapping of a region of chromosome 5p15.33 (TERT-CLPTM1L) suggests a novel locus in TERT and a CLPTM1L haplotype are associated with glioma susceptibility in a Chinese population.
International journal of cancer - 1 Oct 2012
Zhao Yingjie, Chen Gong, Zhao Yao, Song Xiao, Chen Hongyan, Mao Ying, Lu Daru
Abstract excerpt
Two genome-wide association studies (GWAS) have identified 5p15.33 (TERT-CLPTM1L) as one of the susceptible regions for glioma in European background. A replication research of our group highlighted the association signals in the TERT gene of this region in a Chinese Han population. To comprehensively explore the region of glioma association at 5p15.33 and to refine the potential causal variants to a smaller...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.