Article
Role of luteinizing hormone β-subunit gene variants among South Indian women with polycystic ovary syndrome.
Gene - 15 Feb 2012
Dasgupta Shilpi, Sirisha P V S, Neelaveni K, Anuradha K, Sudhakar G, Reddy B Mohan
Abstract excerpt
Abnormal luteinizing hormone (LH) secretion and action are known to affect ovarian steroidogenesis and thus playing a crucial role in manifestation of polycystic ovary syndrome (PCOS). This study is first of its kind to study association of LH β-subunit gene variants with PCOS among South-Indian women. 250 PCOS cases and 299 controls were recruited for the study. All the exons of LH β gene were screened. Allele...
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