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Article

Transcriptional response of zebrafish embryos exposed to neurotoxic compounds reveals a muscle activity dependent hspb11 expression.

PloS one - 1 Jan 2011

Klüver Nils, Yang Lixin, Busch Wibke, Scheffler Katja, Renner Patrick, Strähle Uwe, Scholz Stefan

Abstract excerpt

Acetylcholinesterase (AChE) inhibitors are widely used as pesticides and drugs. Their primary effect is the overstimulation of cholinergic receptors which results in an improper muscular function. During vertebrate embryonic development nerve activity and intracellular downstream events are critical for the regulation of muscle fiber formation. Whether AChE inhibitors and related neurotoxic compounds also provoke...

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Identifiers

PMID: 22205996
DOI: 10.1371/journal.pone.0029063
PMCID: PMC3242778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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