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Network Toxicology and Molecular Docking to Investigate the non-AChE Mechanisms of Organophosphate-Induced Neurodevelopmental Toxicity

2023-07-12

Abstract excerpt

Organophosphate pesticides (OPs) are toxic substances that contaminate aquatic environments, interfere with the development of the nervous system, and induce Neurodevelopmental Toxicity (NDT) in animals and humans. The canonical mechanism of OP neurotoxicity involves the inhibi-tion of acetylcholinesterase (AChE), but other mechanisms non-AChE are also involved and not fully understood. We used network toxicology...

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Literature Corpus work
d426e22a-2f71-5cd0-bd3b-31906aa7a434
DOI
10.20944/preprints202307.0785.v1
Open publication

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