Article
ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure.
PloS one - 1 Jan 2011
Chen Jingchun, Brunzell Darlene H, Jackson Kia, van der Vaart Andrew, Ma Jennie Z, Payne Thomas J, Sherva Richard, Farrer Lindsay A, Gejman Pablo, Levinson Douglas F, Holmans Peter, Aggen Steven H, Damaj Imad, Kuo Po-Hsiu, Webb Bradley T, Anton Raymond, Kranzler Henry R, Gelernter Joel, Li Ming D, Kendler Kenneth S, Chen Xiangning
Abstract excerpt
Individuals with schizophrenia tend to be heavy smokers and are at high risk for tobacco dependence. However, the nature of the comorbidity is not entirely clear. We previously reported evidence for association of schizophrenia with SNPs and SNP haplotypes in a region of chromosome 5q containing the SPEC2, PDZ-GEF2 and ACSL6 genes. In this current study, analysis of the control subjects of the Molecular Genetics...
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