Article
Overexpression of GLUT1 correlates with Kras mutations in lung carcinomas.
Molecular medicine reports - 1 Mar 2012
Sasaki Hidefumi, Shitara Masayuki, Yokota Keisuke, Hikosaka Yu, Moriyama Satoru, Yano Motoki, Fujii Yoshitaka
Abstract excerpt
Glucose is the major source of energy for cells, and glucose transporter 1 (GLUT1) is the most common glucose transporter. GLUT1 has been found to be aberrantly expressed in several tumor types. From the results of the microarray and serial analysis of gene expression (SAGE), GLUT1 transcript expression was found to be higher in clones with mutant Kras alleles. We hypothesized that GLUT1 overexpression might be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
