Article
Regulation of 18F-FDG accumulation in colorectal cancer cells with mutated KRAS.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Dec 2014
Iwamoto Masayoshi, Kawada Kenji, Nakamoto Yuji, Itatani Yoshiro, Inamoto Susumu, Toda Kosuke, Kimura Hiroyuki, Sasazuki Takehiko, Shirasawa Senji, Okuyama Hiroaki, Inoue Masahiro, Hasegawa Suguru, Togashi Kaori, Sakai Yoshiharu
Abstract excerpt
UNLABELLED: KRAS gene mutations occur in approximately 40% of colorectal cancers (CRCs) and are associated with resistance to anti-epidermal growth factor receptor antibody therapy. We previously demonstrated that (18)F-FDG accumulation in PET was significantly higher in CRCs with mutated KRAS th...
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