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Article

GLUT1 mRNA and Protein Expression in Ovarian Borderline Tumors and Cancer

1 Jan 2004

Abstract excerpt

OBJECTIVES: Increased glucose uptake and utilization is a major feature of malignant tumors. Recent studies suggest that the key mechanism of enhanced glucose metabolism in carcinoma cells involves the overexpression of transmembrane glucose transporter proteins (GLUTs). The aim of the present study was to analyze the expression of different GLUT isoforms (GLUT1-4) and to investigate whether alterations in their...

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PMID: 15331928
DOI: 10.1159/000079489

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