Verbascoside is not genotoxic in the ST and HB crosses of the Drosophila wing spot test, and its constituent, caffeic acid, decreases the spontaneous mutation rate in the ST cross.

doi:10.1016/j.fct.2011.12.006

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Article

Verbascoside is not genotoxic in the ST and HB crosses of the Drosophila wing spot test, and its constituent, caffeic acid, decreases the spontaneous mutation rate in the ST cross.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Mar 2012

Santos-Cruz Luis Felipe, Ávila-Acevedo José Guillermo, Ortega-Capitaine Diego, Ojeda-Duplancher Jesús Clemente, Perdigón-Moya Juana Laura, Hernández-Portilla Luis Barbo, López-Dionicio Héctor, Durán-Díaz Angel, Dueñas-García Irma Elena, Castañeda-Partida Laura, García-Bores Ana María, Heres-Pulido María Eugenia

Abstract excerpt

Verbascoside (VB) is a phenylpropanoid isolated from Buddleja species, some of which originate in Mexico, and was first described in the sixteenth century in the codices of Mexican traditional medicine. VB is present in alcohol extracts and is widely used in the north of Mexico as a sunscreen. VB absorbs UV-A and UV-B radiation and has high antioxidant and anti-inflammatory capacities. VB and its constituent...

Topics

Animals
Anti-Inflammatory Agents
Antioxidants
Biotransformation
Caffeic Acids
Chromatography, High Pressure Liquid
Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glucosides

Mutagenicity Tests

Mutation

Phenols

Ultraviolet Rays

Wings, Animal

Source

Open in PubMed

Identifiers

PMID: 22197714
DOI: 10.1016/j.fct.2011.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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